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Marks, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Arm-level data were extracted from primary publications and supplementary materials

Research applications may include copper peptide pathway models, skin matrix research, collagen pathway studies, extracellular matrix research, peptide-metal complex signaling analysis, cellular response models, matrix-associated signaling comparisons, and structure-function evaluation

Neurol Ther (2022) 11(2):86380

Without question, the best type of preventive medicine is an optimized immune system, and a critical strategy to optimize it is by feeding it GSH